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AMACR monoclonal antibody

货号: MB66210

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66210

Product Name :AMACR monoclonal antibody

Swiss-Prot :Q9UHK6

Host :Mouse

Reactivity :Human

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/300)

Background :α-methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives . AMACR has been reported to be a biomarker for prostate cancer (2-4). The expression of AMACR is also related to other types of cancers such as hepatocellular carcinoma , noninvasive bladder cancer , colorectal cancer and gastric adenocarcinoma

Product :Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of AMACR protein.

BiowMW :~ 42 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within human AMACR. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of AMACR expression in Hela (A), HepG2 (B), LNCaP (C) whole cell lysates.

Immunohistochemical analysis of AMACR staining in human prostatic carcinoma formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.