Product Name :Androgen Receptor monoclonal antibody
Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/300)
Background :Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding . This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer .
Product :Mouse IgG2b. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of Androgen Receptor protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DHTR; NR3C4; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4
Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within human Androgen Receptor. The exact sequence is proprietary.
Modification :Unmodification
