Product Name :Mammaglobin A monoclonal antibody
Application_all :IHC (1/100 - 1/300)
Background :Secretoglobins (also called Lipophilins or Mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustinebinding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of Mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B (also designated MGB2, Lipophilin C, LPHC, UGB3 and SCGB2A2) is a reliable diagnostic marker for breast tumors.
Product :Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of Mammaglobin A protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MGB1; UGB2; Mammaglobin-A; Mammaglobin-1; Secretoglobin family 2A member 2
Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within human Mammaglobin A. The exact sequence is proprietary.
Modification :Unmodification
