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CD43 monoclonal antibody

货号: MB65991

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB65991

Product Name :CD43 monoclonal antibody

Swiss-Prot :P16150

Host :Mouse

Reactivity :Human

Applications :IHC

Application_all :IHC (1/100 - 1/300)

Background :CD43, also known as leukosialin and sialophorin, is a type I transmembrane sialylated, negatively charged mucin that is expressed on the surface of most hematopoietic cells. CD43 plays an important role in T lymphocyte function by negatively regulating antigen-specific T cell activation and interfering with cellular adhesion and proliferation. It also has been reported that CD43 is involved in viral clearance. Aberrant expression of CD43 is associated with several diseases, such as Wiskott-Aldrich syndrome and acute leukemia.

Product :Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CD43 protein.

BiowMW :~ 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD43; Leukosialin; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD43

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within human CD43. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of CD43 staining in human anaplastic large cell lymphoma formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.