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HAO1 monoclonal antibody

货号: MB65933

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB65933

Product Name :HAO1 monoclonal antibody

Swiss-Prot :Q9WU19

Host :Mouse

Reactivity :Mouse, Rat

Applications :WB

Application_all :WB (1/1000 - 1/2000)

Background :Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate (PubMed:9891009). The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones (By similarity). Can also catalyze the oxidation glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate (By similarity). Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2.

Product :Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of HAO1 protein.

BiowMW :~ 41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GOX1; HAOX1; Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GOX

Immunogen :Recombinant protein corresponding to mouse HAO1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HAO1 expression in mouse liver (A), rat liver (B) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）