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Fumarase monoclonal antibody

货号: MB65925

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB65925

Product Name :Fumarase monoclonal antibody

Swiss-Prot :P07954

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB (1/1000 - 1/3000), IF/ICC (1/100 - 1/200)

Background :Fumarate hydratase (Fumarase, FH) is canonically regarded as a mitochondrial enzyme of the tricarboxylic acid cycle that catalyzes fumarate to malate. Studies have demonstrated that deficiencies in FH can lead to hereditary leiomyomatosis and renal cell cancer or, in homozygous germline mutations, severe neurological and muscular disorders. There also exists a cytosolic fumarase isoenzyme that is involved in DNA damage repair.

Product :Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Fumarase protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Fumarate hydratase mitochondrial; Fumarase

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence of human Fumarase. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Fumarase expression in 293T (A), HepG2 (B), Hela (C), mouse brain (D), rat brain (E) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）