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Beta3-tubulin monoclonal antibody

货号: MB65881

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB65881

Product Name :Beta3-tubulin monoclonal antibody

Swiss-Prot :Q13509

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/2000 - 1/5000)

Background :Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and maintenance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed:28483977). Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed:28483977).

Product :Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Beta3-tubulin protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TUBB4; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence of human Beta3-tubulin. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Beta3-tubulin expression in Hela (A), mouse brain (B), rat brain (C) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）