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CD90 monoclonal antibody

货号: MB65821

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB65821

Product Name :CD90 monoclonal antibody

Swiss-Prot :P04216

Host :Mouse

Reactivity :Human

Applications :WB IHC-P ICC/IF ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 ELISA: 1/10000

Background :The Thy1/CD90 cell surface antigen is a GPI-anchored, developmentally regulated protein involved in signaling cascades that mediate neurite outgrowth, T cell activation, tumor suppression, apoptosis, and fibrosis. Thy1/CD90 is highly expressed on the surface of adult neurons and is thought to play a role in modulating adhesive and migratory events, such as neurite extension. Decreased Thy1/CD90 mRNA and protein expression is associated with the development of epithelial ovarian cancer, suggesting a role as a putative tumor suppressor gene of human ovarian cancer. Research studies indicate that Thy1/CD90 knockout mice have impaired cutaneous immune responses and abnormal retinal development. Thy1/CD90 is epigenetically regulated or deregulated in some disease states, such as pulmonary fibrosis. The potentially reversible hypermethylation of the Thy1/CD90 promoter offers the possibility of novel therapeutic options in this disease.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes human CD90

BiowMW :~ 18 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Thy-1 membrane glycoprotein; CDw90; Thy-1 antigen; CD90

Immunogen :Purified recombinant fragment of human THY1 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodified

Immunohistochemistry analysis of paraffin-embedded human endometrial cancer tissues using CD90 antibody.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）