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HLA-DR monoclonal antibody

货号: MB65810

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB65810

Product Name :HLA-DR monoclonal antibody

Swiss-Prot :P01903

Host :Mouse

Reactivity :Human

Applications :IF, FC

Application_all :IF (1/50 - 1/200)

Background :Major histocompatibility complex class II (MHC class II) molecules are heterodimeric, transmembrane glycoproteins expressed on the surface of antigen-presenting cells such as macrophages, dendritic cells, and B cells. Expression can also be induced on other cell types through interferon-γ signaling. Prior to being displayed on the cell membrane, MHC class II molecules are loaded with exogenous peptide antigens approximately 15-24 amino acids in length that were derived from endocytosed extracellular proteins digested in the lysosome. Antigen-presentation through MHC class II is required for T cell activation during the immune response to extracellular pathogens. In humans, the MHC class II protein complex is encoded by the human leukocyte antigen gene complex (HLA). HLAs corresponding to MHC class II are HLA-DP, HLA-DM, HLA-DOA, HLA-DOB, HLA-DQ, and HLA-DR.

Product :Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Purification&Purity :The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes human HLA-DR

BiowMW :~ 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HLA-DRA1; HLA class II histocompatibility antigen. DR alpha chain; MHC class II antigen DRA

Immunogen :Native purified human HLA-DR.

Conjugate :Unconjugated

Modification :Unmodification

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-HLA-DR Antibody, followed by anti-mouse IgG PE.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）