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CD62P monoclonal antibody

货号: MB65798

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :MB65798

Product Name :CD62P monoclonal antibody

Swiss-Prot :P16109

Host :Mouse

Reactivity :Human

Applications :IF, FC

Application_all :IF (1/50 - 1/200)

Background :CD62P/P-Selectin is a type-I transmembrane glycoprotein that is largely expressed and stored in intracellular granules by resting platelets, megakaryocytes, and vascular endothelial cells. The restricted expression pattern of CD62P/P-Selectin positions this molecule as a key regulator of hemostasis, thrombosis, and inflammation. Platelets and endothelial cells that become activated in response to proinflammatory cytokines express CD62P/P-Selectin on the cell surface, which serves as an adhesion receptor to facilitate recruitment of leukocytes to sites of inflammation. CD62P/P-Selectin has also been implicated in cancer cell metastasis by promoting the adhesion of tumor cells in circulation to activated platelets and endothelial cells .

Product :Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Purification&Purity :The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes human CD62P

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GMRP; GRMP; P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD antigen CD62P

Immunogen :Native purified human CD62P.

Conjugate :Unconjugated

Modification :Unmodification

Flow cytometric analysis of human platelets treated with Thrombin using Anti-CD62P Antibody, followed by anti-mouse IgG PE.