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CD56 monoclonal antibody

货号: MB65795

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB65795

Product Name :CD56 monoclonal antibody

Swiss-Prot :P13591

Host :Mouse

Reactivity :Human

Applications :IF, FC

Application_all :IF (1/50 - 1/200)

Background :NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains. NCAM mediates neuronal attachment, neurite extension, and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma, and rhabdomyosarcoma. CD56 is commonly used along with CD3 and CD16 to identify human NK cells (Mouse NK cells do not express CD56). Human natural killer cells are CD3-CD56+. The large subset with high CD16 expression are mature cytotoxic natural killer cells, while those with low CD16 expression are immature precursors and cytokine producers.

Product :Mouse IgG2a kappa. Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% sodium azide.

Purification&Purity :The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes human CD56

BiowMW :~ 94 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NCAM; Neural cell adhesion molecule 1; N-CAM-1; NCAM-1; CD antigen CD56

Immunogen :Native purified human CD56.

Conjugate :Unconjugated

Modification :Unmodification

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-CD56 Antibody, followed by anti-mouse IgG PE.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）