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CD11b Rat monoclonal antibody

货号: MB65749

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :MB65749

Product Name :CD11b Rat monoclonal antibody

Swiss-Prot :P11215

Host :Rat

Reactivity :Human

Applications :IF, FC

Application_all :IF (1/50 - 1/200)

Background :Cluster of differentiation molecule 11b (CD11b)/Integrin alpha M (ITGAM) is a transmembrane protein forming heterodimers that are composed of α and β subunits. CD11b is expressed by, and commonly used as a marker for, myeloid lineage cells, including neutrophils, monocytes, macrophages, and microglia. CD11b is phosphorylated at Ser1126 (cytoplasmic tail) in neutrophils. Research has shown that this phosphorylation event plays a role for leukocytes traveling from the blood stream to tissues. Furthermore, genome-wide association studies have linked CD11b to autoimmune diseases, such as systemic lupus erythematous (SLE).

Product :Rat IgG2b kappa. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Purification&Purity :The monoclonal antibody was affinity-purified from rat antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes human CD11b

BiowMW :~ 127 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD11B; CR3A; Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD antigen CD11b

Immunogen :Native purified human CD11b.

Conjugate :Unconjugated

Modification :Unmodification

Flow cytometric analysis of human peripheral blood granulocytes using Anti-CD11b Antibody, followed by anti-mouse IgG PE.