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CD105 monoclonal antibody

货号: MB65746

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB65746

Product Name :CD105 monoclonal antibody

Swiss-Prot :P17813

Host :Mouse

Reactivity :Human

Applications :IF, FC

Application_all :IF (1/50 - 1/200)

Background :CD105/Endoglin is an auxiliary receptor for the TGF-β receptor complex, functioning in related signaling pathways. CD105/Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated CD105/endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos. Mutations in CD105/endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure. The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial cell proliferation as well as a potential therapeutic target in cancer.

Product :Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Purification&Purity :The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes human CD105

BiowMW :~ 70 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :END; Endoglin; CD antigen CD105

Immunogen :Native purified human CD105.

Conjugate :Unconjugated

Modification :Unmodification

Flow cytometric analysis of MCF-7 cells using Anti-CD105 Antibody, followed by anti-mouse IgG PE.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）