Product Name :NBN mouse monoclonal antibody (KU)
Reactivity :Human, Monkey
Applications :10k-ChIP, IF, IHC, WB
Application_all :IHC 1:100, IF 1:100
Background :Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :AT-V1; AT-V2; ATV; NBS; NBS1; P95
Immunogen :Human recombinant protein fragment corresponding to amino acids 461-754 of human NBN (NP_002476) produced in E.coli.
Modification :Unmodification
