Product Name :SQSTM1 mouse monoclonal antibody (KU)
Reactivity :Human, Mouse, Rat
Applications :FC, IF, IHC, WB
Application_all :WB 1:500~2000, IHC 1:150, IF 1:100
Background :This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :A170; OSIL; p60; p62; p62B; PDB3; ZIP3
Immunogen :Full length human recombinant protein of human SQSTM1(NP_003891) produced in HEK293T cell.
Modification :Unmodification