Product Name :MAP2K1 (MEK1) mouse monoclonal antibody (KU)
Reactivity :Human, Dog, Rat, Monkey, Mouse
Applications :IF, IHC, WB
Application_all :WB 1:200~4000, IHC 1:150, IF 1:100
Background :The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CFC3; MAPKK1; MEK1; MKK1; PRKMK1
Immunogen :Full length human recombinant protein of human MAP2K1(NP_002746) produced in HEK293T cell.
Modification :Unmodification
