Product Name :FKBP5 (FKBP51) mouse monoclonal antibody (KU)
Reactivity :Human, Mouse, Rat
Applications :IF, IHC, WB
Application_all :WB 1:2000, IHC 1:50, IF 1:100
Background :The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10
Immunogen :Full-length protein expressed in 293T cell transfected with human FKBP5 expression vector
Modification :Unmodification
