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STAT3 mouse monoclonal antibody (KU)

货号: MB4128
价格 ——
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :MB4128
Product Name :STAT3 mouse monoclonal antibody (KU)
Swiss-Prot :P40763
Host :Mouse
Reactivity :Human, Mouse, Rat
Applications :IHC, WB
Application_all :WB: 1:500, IHC 1:50
Background :The protein encoded by this gene is a member of the STAT protein family. In response to cytokinesand growth factors, STAT family members are phosphorylated by the receptor associated kinases, andthen form homo- or heterodimers that translocate to the cell nucleus where they act astranscription activators. This protein is activated through phosphorylation in response to variouscytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This proteinmediates the expression of a variety of genes in response to cell stimuli, and thus plays a keyrole in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has beenshown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor ofthis protein. Three alternatively spliced transcript variants encoding distinct isoforms have beendescribed
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :IgG1
BiowMW :88.08 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ADMIO; APRF; HIES
Immunogen :Recombinant protein expressed in E.coli corresponding to amino acids 154-175 of human stat3
Conjugate :Unconjugated
Modification :Unmodification

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com