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SSSCA1 mouse monoclonal antibody (KU)

货号: MB4047

价格：￥ ——

货期：现货（1-2个工作日）

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No. :MB4047

Product Name :SSSCA1 mouse monoclonal antibody (KU)

Swiss-Prot :O60232

Host :Mouse

Reactivity :Human

Applications :FC, IF, IHC, WB

Application_all :WB 1:2000, IF 1:100, FLOW 1:100, IHC: 1:150

Background :SSSCA1 (sjogren syndrome/scleroderma autoantigen 1), also known as p27,is a 199 amino acid protein that may play a role in mitosis. Considered a centromere-associated protein, SSSCA1 may induce anti-centromere antibodies. SSSCA1 is phosphorylated upon DNA damage by ATM or ATR. The gene encoding SSSCA1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 27 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein ZNRD2; Autoantigen p27; Sjoegren syndrome/scleroderma autoantigen 1; Zinc ribbon domain-containing protein 2; ZNRD2; SSSCA1

Immunogen :Full length human recombinant protein of human SSSCA1 (NP_006387) produced in HEK293T cell.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of SSSCA1 mouse monoclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(30ug)

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SSSCA1 mouse monoclonal antibody.

Anti-SSSCA1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SSSCA1.