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HOXA3 mouse monoclonal antibody (KU)

货号: MB4042

价格：￥ ——

货期：现货（1-2个工作日）

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No. :MB4042

Product Name :HOXA3 mouse monoclonal antibody (KU)

Swiss-Prot :O43365

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB 1:500~2000

Background :Homeobox protein Hox-D9 (HOXD9) is a sequence-specific transcription factor that is part of a developmental regulatory program that provides cells with specific positional identities on the anterior-posterior axis. HOXD9 is developmentally expressed in structures of either mesodermal or neuro-ectodermal origin, such as developing limbs, gonads, and the central nervous system (1-6). HOXD9 plays a critical role in regulation of limb development, neuronal development, and development of mammary glands and gonads in many organisms (1-6). The HOXD9 gene promoter is found to be hypermethylated and silenced in multiple types of cancer, including breast cancer, melanoma brain metastases, and cholangiocarcinomas (7-9). In addition, HOXD9 expression is increased in other types of cancer, including human glioblastomas and astrocytomas, where expression appears to drive growth of the tumors (10).

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 46 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Homeobox protein Hox-A3; Homeobox protein Hox-1E; HOXA3; HOX1E; 9606 NCBI; Homo sapiens (Human)

Immunogen :Human recombinant protein fragment corresponding to amino acids 40-276 of human HOXA3 (NP_109377) produced in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of HOXA3 mouse monoclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate(30ug)

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）