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NKRF mouse monoclonal antibody (KU)

货号: MB4030

价格：￥ ——

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :MB4030

Product Name :NKRF mouse monoclonal antibody (KU)

Swiss-Prot :O15226

Host :Mouse

Reactivity :Human, Mouse

Applications :WB

Application_all :WB 1:2000

Background :NF-κB Repressing Factor (NKRF) is a constitutively expressed transcription factor that binds to the negative regulatory element within the promotor region of many genes that are transactivated by NF-κB (1). Indeed, research studies have found NKRF to repress transcription of IL-8/CXCL8, iNOS, CXCL10, and IFN-γ (2-4). In addition to regulating the expression of pro-inflammatory factors, NKRF has been shown to play a role in cell survival in the context of proteotoxic stress, through the regulation of rRNA processing and ribosome biogenesis (5).

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG2a

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NF-kappa-B-repressing factor; NFkB-repressing factor; Protein ITBA4; NKRF; ITBA4, NRF; 9606 NCBIHomo sapiens (Human)

Immunogen :Human recombinant protein fragment corresponding to amino acids 1-296 of human NKRF(NP_060014) produced in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of NKRF mouse monoclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate(30ug)

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）