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GEMIN2 mouse monoclonal antibody (KU)

货号: MB4023

价格：￥ ——

货期：现货（1-2个工作日）

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No. :MB4023

Product Name :GEMIN2 mouse monoclonal antibody (KU)

Swiss-Prot :O14893

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :IHC, WB

Application_all :WB 1:2000, IHC 1:150

Background :This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~ 33 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SIP1; SIP1-delta; gem nuclear organelle associated protein 2

Immunogen :Full length human recombinant protein of human GEMIN2(NP_003607) produced in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of GEMIN2 mouse monoclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate(30ug) Lane2:HEK293T whole cell lysate(30ug)

Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-GEMIN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min) (1:150)