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IFIT3 mouse monoclonal antibody (KU)

货号: MB4022

价格：￥ ——

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB4022

Product Name :IFIT3 mouse monoclonal antibody (KU)

Swiss-Prot :O14879

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :FC, IF, WB

Application_all :WB 1:2000, IF 1:100, Flow 1:100

Background :IFIT3 (Interferon-induced protein with tetratricopeptide repeats 3; Retinoic acid-induced gene G protein (RIG-G)) is part of the IFIT family of interferon-stimulating genes known for their antiviral properties (1,2). IFIT3 is widely expressed in T cells, B cells, plasmacytoid and myeloid dendritic cells, neurons, and kidney cells (3,4). In response to RNA viral infection, IFIT3 regulates IRF3 activation through interaction with TBK1 and MAVS on the mitochondrion (5). IFIT3 also interacts with IFIT1, leading to inhibitory activity against viral RNA lacking the 2′-O-methylation in the cap structure (6).

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG1

BiowMW :~60-65 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Gem-associated protein 2; Gemin-2; Component of gems 2; Survival of motor neuron protein-interacting protein 1 (SMN-interacting protein 1); GEMIN2; SIP1

Immunogen :Full length human recombinant protein of human IFIT3 (NP_001540) produced in HEK293T cell.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of IFIT3 mouse monoclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate(30ug)； Lane2:The Lung tissue lysate of mouse(30ug)； Lane3:The Liver tissue lysate of Rat(30ug)