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Rad23B (5H1) monoclonal antibody

货号: MB0186
价格 1350
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :MB0186
Product Name :Rad23B (5H1) monoclonal antibody
Swiss-Prot :P54727
Host :Mouse
Reactivity :Human,Mouse,Rat,Monkey
Applications :WB ICC IHC
Application_all :WB: 1:1000 IHC/ICC: 1:50~200
Background :The RAD23 genes (RAD23A and RAD23B), which encode the human Rad23 proteins, are crucial for excision-repair of UV-damaged DNA. RAD23 genes resemble the other DNA repair genes, RAD2, RAD6, RAD7, RAD18 and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis. Rad23 is a nuclear protein containing an ubiquitin-like domain required for biological functions. The protein, which is highly conserved, is involved in nucleotide excision repair (NER) that associates with the proteasome via its N-terminus. The C-terminal ubiquitin-associated domain of Rad23 is evolutionarily conserved from yeast to humans. Rad23 may also act as a regulator for the activity of the 26S Proteasome.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :This antibody detects endogenous levels of Rad23B and does not cross-react with related proteins.
BiowMW :Predicted band size:55KDa Observed band size:55KDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :UV excision repair protein RAD23 homolog B; HR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58; RAD23B
Immunogen :Purified recombinant human Rad23B protein fragments expressed in E.coli.
Conjugate :Unconjugated
Modification :Unmodification
Western blot detection of Rad23B in K562,SW480,CHO-K1,3T3 and COS7 cell lysates using Rad23B mouse mAb (1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded Prostate Cancer using Rad23B mouse mAb (1/100 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).
Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-Rad23B antibody (dilution 1:100).

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com