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SMYD1 monoclonal antibody

货号: MB0166

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB0166

Product Name :SMYD1 monoclonal antibody

Swiss-Prot :Q8NB12

Host :Mouse

Reactivity :Rat

Applications :WB

Application_all :WB: 1:1000~2000

Background :SMYD1 (SET and MYND domain-containing protein 1), also known as BOP, ZMYND18 or ZMYND22, is a nuclear and cytoplasmic protein that contains one SET domain and one MYND-type zinc finger. Expressed specifically in cardiac and skeletal muscle, SMYD1 functions as a transcription factor that is essential for cardiac morphogenesis and proper cardiomyocyte differentiation. SMYD1 interacts with the histone deacetylases HDAC1, HDAC2 and HDAC3 and, through this interaction, acts as a histone deacetylase-dependent transcriptional repressor. Defects or deletions in the gene encoding SMYD1 lead to retarded maturation of ventricular cardiomyocytes, further implicating SMYD1 as a crucial component of normal cardiac development.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of SMYD1 and does not cross-react with related proteins

BiowMW :Predicted band size:56KDa Observed band size:56KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD8 beta opposite zinc finger; MYND domain containing 18; BOP; KMT3D; ZMYND18; ZMYND22; SMYD1

Immunogen :Recombinant full length Human SMYD1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of SMYD1 in rat skeletal muscle lysates and using SMYD1 antibody (1:2000 diluted) .

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）