产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Phostensin monoclonal antibody

货号: MB0157

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0157

Product Name :Phostensin monoclonal antibody

Swiss-Prot :Q6NYC8

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB: 1:200~1000

Background :In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases, specifically PP1 (protein phosphhatase 1), which is targeted to different substrates throughout the cell. Phostensin, also known as KIAA1949, is a 613 amino acid protein that localizes to both the cytoplasm and the cytoskeleton. Expressed predominately in spleen, ovary, lung and liver tissue, phostensin functions as a regulatory subunit that interacts with and targets PP1 to F-Actin in the cytoskeleton. Two isoforms of phostensin exist due to alternative splicing events.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of Phostensin and does not cross-react with related proteins

BiowMW :Predicted band size:120KDa Observed band size:120KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HKMT1098; KIAA1949; Protein phosphatase 1 F actin cytoskeleton targeting subunit.; PPP1R18;

Immunogen :Recombinant full length Human Phostensin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PPP1R18 in Hela, Raji, Ramos&Leucocyte cell lysates and using PPP1R18 antibody (1:200 diluted) .

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）