Product Name :SMYD2 monoclonal antibody
Application_all :WB: 1:1000
Background :SMYD2 (SET and MYND domain containing 2), also known as KMT3C, HSKM-B or ZMYND14, is a 433 amino acid protein that contains one SET domain and one MYND-type zinc finger. Expressed at high levels in liver, heart, kidney, ovary and brain, SMYD2 functions as a lysine methyltransferase that, via methylation of p53, may play a role in repressing p53-mediated transcriptional regulation. The gene encoding MSYD2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :This antibody detects endogenous levels of SMYD2 and does not cross-react with related proteins
BiowMW :Predicted band size:50KDa
Observed band size:50KDa
Note :For research use only, not for use in diagnostic procedure.
Pathway :Epigenetic Writers and Erasers of Histone H3,
Alternative Name :HSKM-B; Histone methyltransferase SMYD2,EC=2.1.1.43; Lysine N-methyltransferase 3C; SET and MYND domain-containing protein 2; KMT3C; HSKM-B; ZMYND14
Immunogen :Recombinant full length Human SMYD2.
Modification :Unmodification
