产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Crk2 monoclonal antibody

货号: MB0130

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0130

Product Name :Crk2 monoclonal antibody

Swiss-Prot :P46108

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB: 1:1000

Background :Crk I and Crk II are encoded by the same gene, which undergoes alternative splicing to yield these two proteins, but differ in their biological activities. Crk II has less transforming activity than Crk I, although both Crk I and Crk II bind to many tyrosine-phosphorylated proteins that bind to GRB2. In addition, Crk II becomes rapidly tyrosine-phosphorylated in response to stimulation with insulin-like growth factor I (IGF-I) and might be involved in the IGF-I receptor signalling pathway.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Crk2 mAb detects endogenous levels of Crk2 protein.

BiowMW :Predicted band size:34kDa Observed band size:34kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Adapter molecule crk; Proto-oncogene c-Crk; p38 CRK; CRK; CRKII

Immunogen :Recombinant full length Human Crk2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CRK in LNCAP, A431, MCF7&HT1080 cell lysates using CRK antibody (1:1000 diluted) .

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）