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CHRDL1 monoclonal antibody

货号: MB0127

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB0127

Product Name :CHRDL1 monoclonal antibody

Swiss-Prot :Q9BU40

Host :Mouse

Reactivity :Human,Mouse,Rat

Applications :WB ICC

Application_all :WB: 1:1000 ICC: 1:300

Background :This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation By similarity. May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CHRDL1 mAb detects endogenous levels of CHRDL1 protein.

BiowMW :Predicted band size:57kDa Observed band size:57kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Neuralin-1 Neurogenesin-1 Ventroptin; CHL; VOPT; NRLN1; dA141H5.1

Immunogen :Recombinant full length Human CHRDL1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CHRDL1 in Rat kidney tissue lysates using CHRDL1 antibody (1:1000 diluted) .

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）