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CHD4 monoclonal antibody

货号: MB0126

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0126

Product Name :CHD4 monoclonal antibody

Swiss-Prot :Q14839

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB: 1:1000

Background :The product of this gene belongs to the SNF2/RAD54 helicase family.It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression.Patients with dermatomyositis develop antibodies against this protein.Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CHD4 mAb detects endogenous levels of CHD4 protein.

BiowMW :Predicted band size:260KDa Observed band size:260KDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :ATP-Dependent Chromatin Remodeling Complexes,DNA Methylation,

Alternative Name :ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-beta; Mi-2b; Mi2-BETA; CHD4

Immunogen :Recombinant full length Human CHD4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CHD4 in K562, HelaNE, HL-60, MOLT-4, Jurkat & 293 cell lysates using CHD4 antibody (1:1000 diluted) .

VGLL3 modulates chemosensitivity through promoting DNA double-strand break repair

Journal10.1126/sciadv.adr2643

ApplicationWB

IF11.7

SpeciesHuman

PMID39383226