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PP1A / PPP1CA (N-terminus) monoclonal antibody

货号: MB0084

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB0084

Product Name :PP1A / PPP1CA (N-terminus) monoclonal antibody

Swiss-Prot :P62136

Host :Mouse

Reactivity :Human

Applications :WB IHC ICC

Application_all :WB: 1:1000 ICC: 1:200~400 IHC: 1:500

Background :Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role. in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of PP1A (N-terminus) and does not cross-react with related proteins

BiowMW :Predicted band size:38KDa Observed band size:38KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; PP-1A; PPP1CA; PPP1A

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human PP1A / PPP1CA.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PPP1CA in MCF7, K562, Hela, HEPG2 &Jurkat cell lysates using PPP1CA antibody (1:1000 diluted) .

IHC of paraffin-embedded human breast cancer using anti- PPP1CA diluted 1/500-1/1000.

Immunocytochemistry stain of Hela using PPP1CA antibody (1:300).

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