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PPAR-γ (C-terminus) monoclonal antibody

货号: MB0080

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB0080

Product Name :PPAR-γ (C-terminus) monoclonal antibody

Swiss-Prot :P37231

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB: 1:500

Background :PPAR gamma is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR gamma activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPAR gamma may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPAR gamma2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPAR gamma2 gene maybe correlated with abdominal obesity in type 2 diabetes.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of PPAR gamma (C-terminus) and does not cross-react with related proteins

BiowMW :~53/57kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Nuclear Receptor Signaling,MTOR signaling,

Alternative Name :CIMT1; GLM1; NR1C3; Nuclear receptor subfamily 1 group C member 3; OTTHUMP00000185032; OTTHUMP00000185036; Peroxisome proliferator activated nuclear receptor gamma variant 1; Peroxisome proliferator activated receptor gamma 1; Peroxisome Proliferator Acti

Immunogen :Synthetic peptide, corresponding to amino acids C-terminus of Human PPAR-γ.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PPARγ fragment in CHO-K1 cell lysate (A) and CHO-K1 transfected by pEGFP-C1-PPARγ (B) cell lysate using PPARγ mouse mAb (1:500 diluted).Predicted band size: 53kDa.Observed band size:53kDa.

The influence of maternal dietary fat on the fatty acid composition and lipid metabolism in the subcutaneous fat of progeny pigs

JournalMeat Science

ApplicationWB

IF5.209

SpeciesSows

PMID
Lipopolysaccharide significantly influences the hepatic triglyceride metabolism in growing pigs

JournalLipids in Health and Disease

ApplicationWB

IF2.906

SpeciesPig

PMID26121977
PPARγ, FAS, HSL mRNA and protein expression during Tan sheep fat-tail development

JournalElectronic Journal Of Biotechnology

ApplicationWB

IF2.04

SpeciesSheep

PMID