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CBX5 monoclonal antibody

货号: MB0063

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB0063

Product Name :CBX5 monoclonal antibody

Swiss-Prot :P45973

Host :Mouse

Reactivity :Human,Mouse

Applications :WB ICC

Application_all :WB: 1:1000 ICC: 1:100~500

Background :Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members (α, β, and γ) are primarily associated with centromeric heterochromatin; however, HP1β and γ also localize to euchromatic sites in the genome. HP1 proteins are approximately 25 kDa in size and contain a conserved amino-terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain. The chromodomain facilitates binding to histone H3 tri-methylated at Lys9, a histone "mark" closely associated with centromeric heterochromatin.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of CBX5 and does not cross-react with related proteins

BiowMW :Predicted band size:22KDa Observed band size:25KDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Examples of Crosstalk Between Post-translational Modifications,DNA Methylation,

Alternative Name :Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha; HP1α; CBX5; HP1A

Immunogen :Recombinant full length Human CBX5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CBX5 in MCF7, 293T, HelaNE, 3T3, C6, COS7&Mouse brain lysates and using CBX5 antibody (1:1000 diluted) .

Immunocytochemistry stain of Hela using CBX5 antibody (1:300).

免疫沉淀（IP）