Product Name :EAR2 polyclonal antibody(KU)
Application_all :WB: 1:2000~1:5000
Background :EAR2 (v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2)protein binds a cis enhancer element (TGACCT motif) upstream of the reningene and represses renin gene transcription. EAR2 also contributes togonadotropin-dependent derepression of LHR promoter activity in granulosacells. EAR2 mRNA is abundant in the liver, and EAR2 protein localizes to thenucleus of As4.1 cells.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :EAR2 polyclonal antibody detects endogenous levels of EAR2 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2; NR2F6; EAR2; ERBAL2
Immunogen :Synthetic peptide, corresponding to Human EAR2.