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COUP-TF II polyclonal antibody（KU）

货号: GCP118

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :GCP118

Product Name :COUP-TF II polyclonal antibody（KU）

Swiss-Prot :P24468

Host :Rabbit

Reactivity :Human

Applications :WB IHC

Application_all :WB: 1:1000~1:2000 IHC: 1:50~1:200

Background :Chicken ovalbumin upstream promoter transcription factor (COUP-TF) belongs to the NR2 subfamily of the nuclear hormone receptor family. COUP-TFI and COUP-TFII are two of the well-characterized members in the NR2 subfamily. These two members are highly conserved in their two zinc-finger DNA binding domains (DBD) and the ligand binding domain (LBD), and function as repressors or activators of downstream target genes to regulate different biological processes . COUP-TFI and II bind to 5'-AGGTCA-3' motif palindromes, either directly or indirectly, through heterodimer formation with other proteins (e.g. RXRs) to regulate downstream target gene expression. COUP-TFI is involved in neuronal development, tissue patterning, and differentiation . COUP-TFII has been shown to be involved in angiogenesis, glucose homeostasis, and mesenchymal cell commitment.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COUP-TF II polyclonal antibody detects endogenous levels of COUP-TF II protein.

BiowMW :~ 47 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :COUP transcription factor 2; Apolipoprotein A-I regulatory protein 1; COUP transcription factor II; COUP-TF2; Nuclear receptor subfamily 2 group F member 2; ARP-1; COUP-TF II; NR2F2; ARP1; TFCOUP2

Immunogen :Synthetic peptide, corresponding to Human COUP-TF II.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of COUP-TF II polyclonal antibody at 1:1000 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:HepG2 whole cell lysate(40ug)