Product Name :VCAM1 Rabbit monoclonal antibody
Reactivity :Human,Mouse,Rat, Zebra fish
Applications :WB IF IHC ICC
Application_all :WB: 1:200-1:1000
IHC/ICC/IF: 1:20-1:200
Background :The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2α1 and B2αM integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM) -like protein and is deleted in 66% of patients with Kallmann's syndrome, anosmia with secondary hypogonadism .
Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :VCAM1 Rabbit monoclonal antibody detects endogenous levels of VCAM1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD106; L1CAM
Immunogen :KLH conjugated synthetic peptide derived from human VCAM-1: 651-739/739
Modification :Unmodification