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Cathepsin L1 HC (T288) polyclonal antibody（KU）

货号: BS9330

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9330

Product Name :Cathepsin L1 HC (T288) polyclonal antibody（KU）

Swiss-Prot :P07711

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin L (also designated major excreted protein, MEP or CATL) is a member of the peptidase C1 family and has been identified as a protein that is most closely related to cathepsin H. Cathepsin L is a lysosomal cysteine proteinase that mediates intracellular protein catabolism for collagen, elastin and α-1 protease inhibitor. Cathepsin L is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene. Transformed mouse fibroblasts stimulated by growth factors or tumor promoters secrete a form of cathepsin L.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cathepsin L1 HC (T288) polyclonal antibody detects endogenous levels of Cathepsin L1 HC protein.

BiowMW :~ 26 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cathepsin L1; Cathepsin L; Major excreted protein; MEP; Cathepsin L1 heavy chain; Cathepsin L1 light chain; CTSL; CTSL1

Immunogen :Synthetic peptide, corresponding to amino acids 230-288 of Human Cathepsin L1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Cathepsin L1 HC (T288) polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:L02 whole cell lysate(10ug) Lane3:Beas-2B whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug) Lane5:PC12 whole cell lysate(40ug)