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Cathepsin H HC (N292) polyclonal antibody（KU）

货号: BS9327

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9327

Product Name :Cathepsin H HC (N292) polyclonal antibody（KU）

Swiss-Prot :P09668

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:1000~1:2000

Background :Cathepsin H (also designated N-benzoylarginine-β-naphthylamide hydrolase, aleurain, cathepsin B3 or cathepsin BA) is a lysosomal cysteine proteinase that mediates degradation of lysosomal proteins. Cathepsin H is a disulfidelinked heavy and light chain dimer produced from a single precursor protein. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Elevated levels of cathepsin H correlates with malignant progression of prostate tumors. Two transcript variants encoding different isoforms have been found for this gene. Full-length and truncated cathepsin H [12 amino acid deletion in the signal peptide region (CTSH∆10-21)] are expressed in prostate tissues, LNCaP, PC-3 and DU-145 prostate cancer cell lines. Cathepsin H mediates maturation of the biologically active surfactant protein-B (SP-B) peptide.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cathepsin H HC (N292) polyclonal antibody detects endogenous levels of Cathepsin H HC protein.

BiowMW :~ 26 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Pro-cathepsin H; Cathepsin H mini chain; Cathepsin H; Cathepsin H heavy chain; Cathepsin H light chain; CTSH; CPSB

Immunogen :Synthetic peptide, corresponding to amino acids 240-292 of Human Cathepsin H HC.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Cathepsin H HC (N292) polyclonal antibody at 1:1000 dilution Lane1:SGC7901 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:The Lung tissue lysate of Mouse(40ug) Lane4:The Lung tissue lysate of Rat(40ug) Lane5:HuT78 whole cell lysate(40ug)