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Cathepsin A 20k (M327) polyclonal antibody（KU）

货号: BS9322

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9322

Product Name :Cathepsin A 20k (M327) polyclonal antibody（KU）

Swiss-Prot :P10619

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The cathepsin family of proteolytic enzymes include several diverse classes of proteases. Cathepsins B, L, H, K, S and O comprise the cysteine protease class. Cathepsins D and E comprise the aspartyle protease class. The serine protease class includes cathepsin G. Cathepsins function in cellular metabolism and participate in peptide biosynthesis and protein degradation. Cathepsin A, a serine carboxypepidase, exists in a high molecular weight lysosomal complex with β-galactosidase (β-Gal) and α-neuraminidase (Neu1). Cathepsin A functions to protect β-Gal and Neu1 from intralysosomal proteolysis. Deficiencies in cathepsin A lead to deficiencies in β-Gal and Neu1. The gene encoding human cathepsin A maps to chromosome 20q13.12. Mutations in this gene cause glactosialidosis, a lysosomal storage disorder resulting from the β-Gal and Neu1 deficiencies.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cathepsin A 20k (M327) polyclonal antibody detects endogenous levels of Cathepsin A 20k protein.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Lysosomal protective protein; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; Protective protein cathepsin A; PPCA; Protective protein for beta-galactosidase; Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain; CTSA; PPGB

Immunogen :Synthetic peptide, corresponding to amino acids 327-380 of Human Cathepsin A.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Cathepsin A 20k (M327) polyclonal antibody at 1:500 dilution Lane1:Panc1 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug)