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IL-11Rα (D361) polyclonal antibody

货号: BS9265

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS9265

Product Name :IL-11Rα (D361) polyclonal antibody

Swiss-Prot :Q14626

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The pleiotropic cytokine, IL-11, has been shown to have proliferative and differentiation effects on lymphopoietic, myeloid and erythroid cells. IL-11 also has the inhibiting effect of repressing adipogenesis in vitro. The IL-11α receptor, IL-11Rα, is a member of the class 1 subgroup of the cytokine receptor family and exhibits structural similarity to the α subunits of the human ciliary neurotrophic factor (CNTF) and the mouse IL-6 receptor. It is speculated that the IL-11Rα regulates the proliferation and/or differentiation of skeletogenic progenitor and mesenchymal cells. Coexpression of gp130 and IL-11α is necessary for high-affinity binding of IL-11 to IL-11Rα. It has also been found that coexpression of IL-11Rα and gp130 is required for proper stimulation of Ba/F3 cells to differentiate into macrophage in response to IL-11.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-11Rα(D361) polyclonal antibody detects endogenous levels of IL-11Rα protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; IL11RA

Immunogen :Synthetic peptide, corresponding to amino acids 330-380 of Human IL-11Rα.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IL-11Rα (D361) pAb at 1:500 dilution Lane1:A375 whole cell lysate(40ug) Lane2:K562 whole cell lysate(40ug) Lane3:The Muscle tissue lysate of Mouse(30ug) Lane4:The Heart tissue lysate of Rat(30ug)