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Plasminogen (Y233) polyclonal antibody（KU）

货号: BS9229

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9229

Product Name :Plasminogen (Y233) polyclonal antibody（KU）

Swiss-Prot :P00747

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the fibrinolytic system. Within the fibrinolytic cascade, the serine proteinases urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) activate the proenzyme plasminogen by cleaving plasminogen to form the fibrinolytically active enzyme plasmin. The enzyme plasmin consists of a heavy chain of 561 amino acids, which originates from the N-terminus of plasminogen, and a light chain of 230 amino acid residues, which is derived from the C-terminus of plasminogen. Plasmin is a proangiogenic proteinase that is capable of degrading a variety of extracellular matrix proteins and that facilitates endothelial cell migration and angiogenesis. In the presence of free sulfhydryl donors (FSD), plasmin undergoes auto-proteolysis and is converted to the enzyme angiostatin, which blocks angiogenesis and neovascularization and can inhibit the growth of primary and metastatic tumors.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Plasminogen (Y233) polyclonal antibody detects endogenous levels of Plasminogen protein.

BiowMW :~ 100 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Plasminogen; Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; PLG

Immunogen :Synthetic peptide, corresponding to amino acids 201-250 of Human Plasminogen.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Plasminogen (Y233) pAb at 1:500 dilution Lane1:L02 whole cell lysate(10ug) Lane2:The Testis tissue lysate of Mouse(40ug) Lane3:The Testis tissue lysate of Rat(40ug) Lane4:K562 whole cell lysate(20ug)

Cerebrospinal Fluid Proteomic Profiles in Patients with Postherpetic Neuralgia

JournalJOURNAL OF PROTEOME RESEARCH

ApplicationWB

IF4.4

SpeciesHuman

PMID37966014