产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

ROR2 (E524) polyclonal antibody（KU）

货号: BS9218

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9218

Product Name :ROR2 (E524) polyclonal antibody（KU）

Swiss-Prot :Q01974

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain, distally located serine-threonine-rich domains, an extracellular immunoglobulin-like domain, a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt1 and Wnt3, regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder, brachydactyly type B1 or the autosomal recessive skeletal disorder, Robinow syndrome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ROR2 (E524) polyclonal antibody detects endogenous levels of ROR2 protein.

BiowMW :~ 135 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BDB; BDB1; Brachydactyly type B; Neurotrophic tyrosine kinase; receptor related 2; NTRKR2;

Immunogen :Synthetic peptide, corresponding to amino acids 500-550 of Human ROR2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ROR2 (E524) pAb at 1:1000 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:A549 whole cell lysate(30ug) Lane4:HEK293T whole cell lysate(40ug)