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CD272 (W153) polyclonal antibody

货号: BS9212

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9212

Product Name :CD272 (W153) polyclonal antibody

Swiss-Prot :Q7Z6A9

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :B and T lymphocyte attenuator (BTLA,CD272) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are co-inhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T cell activation by propagating inhibitory signals through BTLA. The BTLA-HVEM interaction is conserved between mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD272 (W153) polyclonal antibody detects endogenous levels of CD272 protein.

BiowMW :~ 33 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD272; BTLA

Immunogen :Synthetic peptide, corresponding to amino acids 120-176 of Human CD272.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD272 polyclonal antibody at 1:1000 dilution Lane1:THP-1 whole cell lysate(37ug) Lane2:The Spleen tissue lysate of Rat(32ug) Lane3:The Spleen tissue lysate of Mouse(36ug) Lane4:The peripheral blood cell lysateof Rat(36ug) Lane5:The peripheral blood cell lysate of Mouse(36ug)