Product Name :Kv4.1 (N588) polyclonal antibody（KU）
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
Background :The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming α-subunits (KVα), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2 and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Kv4.1 (N588) polyclonal antibody detects endogenous levels of Kv4.1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Potassium voltage-gated channel subfamily D member 1; Voltage-gated potassium channel subunit Kv4.1; KCND1
Immunogen :Synthetic peptide, corresponding to amino acids 559-610 of Human KV4.1.
Modification :Unmodification
