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LAMP2a polyclonal antibody

货号: BS90788

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS90788

Product Name :LAMP2a polyclonal antibody

Swiss-Prot :P13473

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity :LAMP2a polyclonal antibody detects endogenous levels of LAMP2a protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; LGP-96; CD107b; LAMP2

Immunogen :Synthetic peptide, corresponding to Human LAMP2a.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of LAMP2a polyclonal antibody at 1:500 dilution LaneA:A375 cell membrane lysate(40ug) LaneB:DLD cell membrane lysate(40ug) LaneC:The Lung tissue lysate of Mouse(40ug) LaneD:The Liver tissue lysate of Mouse(40ug) LaneE:The Lung tissue lysate of Rat(40ug) LaneF:The Liver tissue lysate of Rat(40ug)