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DKK1 polyclonal antibody

货号: BS90412

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS90412

Product Name :DKK1 polyclonal antibody

Swiss-Prot :O94907

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB 1:500 - 1:1000

Background :This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DKK1 polyclonal antibody detects endogenous levels of DKK1 protein.

BiowMW :~ 28-45 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Wntβ catenin signaling

Alternative Name :DKK1;DKK-1;SK

Immunogen :Recombinant fusion protein containing a sequence corresponding to amino acids 71-266 of human DKK1 (NP_036374.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using DKK1 antibody at 1:3000 dilution.

The Biological Effects of Dickkopf1 on Small Cell Lung Cancer Cells and Bone Metastasis

JournalOncology Research

ApplicationWB

IF5.574

SpeciesHuman

PMID28081731
Chronic noise exposure exacerbates AD-like neuropathology in SAMP8 mice in relation to Wnt signaling in the PFC and hippocampus

JournalScientific Reports

ApplicationWB

IF4.011

SpeciesMouse

PMID30279527