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CYP3A4 polyclonal antibody

货号: BS90368

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS90368

Product Name :CYP3A4 polyclonal antibody

Swiss-Prot :P08684

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF/ICC

Application_all :WB 1:500 - 1:2000 IF/ICC 1:50 - 1:200

Background :CYP3A, the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of the clinical test & lt; RTI ID = 0.0 & gt; (cYP3A) genes encode monooxygenases-enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A family members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster maps to gene locus 7q22.1 and consists of four genes (CYP3A4, CYP3A5, CYP3A7 and CYP3A43) and two pseudogenes ( CYP3A4 is abundant in the endoplasmic reticulum of liver cells and upper intestinal enterocytes. CYP3A4 expression is isducible by glucocorticoids pharmacological agents.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity :CYP3A4 polyclonal antibody detects endogenous levels of CYP3A4 protein.

BiowMW :~ 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CYP3A4; CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1

Immunogen :Recombinant fusion protein containing a sequence corresponding to amino acids 244-503 of human CYP3A4 (NP_059488.2).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of HeLa cells using CYP3A4 antibody at dilution of 1:100 (40x lens).