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RASSF5 polyclonal antibody

货号: BS8875

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8875

Product Name :RASSF5 polyclonal antibody

Swiss-Prot :Q8WWW0

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RASSF5 polyclonal antibody detects endogenous levels of RASSF5 protein.

BiowMW :~ 37, 45kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ras association domain-containing protein 5; New ras effector 1; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RAPL; RASSF5; NORE1, RAPL

Immunogen :Recombinant full length Human RASSF5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using RASSF5 antibody.