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NLRC4 polyclonal antibody

货号: BS8872

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8872

Product Name :NLRC4 polyclonal antibody

Swiss-Prot :Q9NPP4

Host :Rabbit

Reactivity :Rat

Applications :ELISA IHC ICC IF

Application_all :ELISA 1:5000-10000 IHC 1:100-500 ICC 1:100-500 IF 1:100-500

Background :This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NLRC4 polyclonal antibody detects endogenous levels of NLRC4 protein.

BiowMW :~ 116 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Inflammasonme Signaling,Necrotic Cell Death,

Alternative Name :LRR; CARD 12; CARD; CARD LRR and NACHT containing protein 1; CARD LRR and NACHT containing protein; CARD12; Caspase recruitment domain containing protein 12; Caspase recruitment domain-containing protein 12; CLAN 1; CLAN A; CLAN; CLAN B; CLAN C; CLAN D; Clan protein; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR 2.1; CLR2.1; ICE protease activating factor; Ice protease-activating factor; Ipaf; NLR family CARD domain containing 4; NLR family CARD domain-containing protein 4; NLRC 4; NLRC4; NLRC4_HUMAN; NACHT-containing protein

Immunogen :KLH conjugated synthetic peptide derived from human CARD12:401-500/1024.

Conjugate :Unconjugated

Modification :Unmodification

Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NLRC4) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C.