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RUNX3 polyclonal antibody

货号: BS8826

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS8826

Product Name :RUNX3 polyclonal antibody

Swiss-Prot :Q13761

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:100

Background :This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :49KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RUNX3;AML2;CBFA3;PEBP2aC

Immunogen :Recombinant fusion protein of human RUNX3(NP_004341.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of Mouse stomach, using RUNX3 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 180s.

Immunofluorescence analysis of MCF-7 cells using RUNX3 antibody . Blue: DAPI for nuclear staining.

TET-Mediated Sequestration of miR-26 Drives EZH2 Expression and Gastric Carcinogenesis

JournalCancer Research

ApplicationWB

IF9.727

SpeciesHuman

PMID28923852